Create a new Web Application and Site Collection with Powershell

Below is a simple PowerShell script you can use to create a new Web Application and thereafter a new Site Collection in that web app:

Add-PSSnapin Microsoft.SharePoint.PowerShell -ErrorAction "SilentlyContinue" | Out-Null

$name = "SharePoint 2010 Intranet"

$port = 80

$url = "http://intranet.philsdevdomain.com"

$appPoolName = "SharePointAppPool"

$appPoolAccount = Get-SPManagedAccount "philsdevdomain\spservice"

$databasename = "SharePoint_Intranet_Content_001"

New-SPWebApplication

-Name $name

-Port $port

-HostHeader $HostHeader

-URL $url

-ApplicationPool $appPoolName

-ApplicationPoolAccount $appPoolAccount

-DatabaseName $databasename

$scOwner = "philsdevdomain\phil"

$template = "STS#1"

New-SPSite -URL $url -Name $name -OwnerAlias $scOwner -Template $template

Remove-PSSnapin Microsoft.SharePoint.Powershell

Note: New-SPWebApplication will need to be on one line, and "STS#1" represents "Blank Site"